The Tuberous Sclerosis Alliance explains that TSC is a genetic condition – meaning it’s in the family bloodlines. The disease can be inherited from just 1-parent with the condition, or it can “result from a spontaneous genetic mutation,” it adds.
The source also notes that children have a 50-percent chance of inheriting TSC if 1-parent has it. However, while it’s considered a genetic condition, “only one-third of TSC cases are known to be inherited,” says the alliance. The other cases are the result of the aforementioned genetic mutation during conception or early development that’s unpredictable, it adds.